(+/-)-1-AMINO-TRANS-3-PHOSPHONO-CYCLOPEN TANE CARBO

(+/-)-1-AMINO-TRANS-3-PHOSPHONO-CYCLOPEN TANE CARBO

103439-17-4

Synoyms:Z-CYCLOPENTYL-AP4;103439-17-4;cis-(+/-)-1-Amino-3-phosphonocyclopentane carboxylic acid;AKOS024457506;(+/-)-1-AMINO-TRANS-3-PHOSPHONO-CYCLOPEN TANE CARBO
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Group III mGlu receptor agonist that exhibits higher potency at mGlu 4 than mGlu 8 (EC 50 values are 49 and 124 μ M respectively) with no activity at mGlu 7 . Selectively inhibits synaptic activity in the lateral perforant pathway (IC 50 values are 130 and 1859 μ M in the lateral and medial perforant pathways respectively). Conformationally restrained analog of L-AP4 (Cat No. 0103 ).

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